Metazoa Expression Portal
MetazExp is a web-based platform for comparative analysis of gene expression and alternative splicing in ~53,000 uniformly processed publicly available RNA-seq experiments from 72 metazoa. It has following highlights:
I. Annotation improvement Gene models are improved to provide more alternative isoforms, especially for non-mode species. What’s more, it includes alternative splicing event annotation that are not presented in reference genome annotation.
II. Sample curation The sample information including strain, genotype, tissue, development and treatment, are curated manually for users to better explore biology significances associated with change of gene expression or alternative splicing.
III. Multi-way retrieval Gene expression or alternative splicing can be searched with gene identifier, symbol and various functional terms such as gene ontology, family, and KEGG pathway, as well as gene sequence similarity using blast program.
IV. Expression analysisThe differential(example) and specific(example ) expression analysse are implemented for users to find genes and alternative splicing events with biological significances.
V. High customizability Users can freely specify different metrics to estimate gene expression and alternative splicing profiles and choose different methods in differential/specifical expression and enrichment analyses.
VI Abundance diagram and external links It provides abundant charts to summarize retrieval and analysis results. It also provides links to external important resources, such as Ensembl, NCBI, Pfam, GO, KEGG, UniProt, Pubmed,SRA and GEO.
It is worth noting that all data deposited in MetazExp are available for download to analyze locally. Please send feedbacks and/or questions to (
Drosophila melanogaster
(fruit fly)
Aedes aegypti
(yellow fever mosquito)
Apis mellifera
(honey bee)
Bombyx mori
Tribolium castaneum
(red flour beetle)
Acyrthosiphon pisum
(pea aphid)
Caenorhabditis elegans
Brugia malayi
(malayan filaria)
Schistosoma mansoni
(blood fluke)